MUDr. Roman Hakl, Ph.D.

2025

• Angioedém jako nežádoucí účinek léčby různými farmaky

  BAROŠ Jan HAKL Roman PEŠÁK Sáva CHOVANCOVÁ Zita

  Article in Periodical

  VNITŘNÍ LÉKAŘSTVÍ - ČASOPIS ČESKÉ INTERNISTICKÉ SPOLEČNOSTI A SLOVENSKEJ INTERNISTICKEJ SPOLOČNOSTI, year: 2025, volume: 2025, edition: 8

• Case report: challenges in a long-term prophylaxis in hereditary angioedema (HAE)

  BAROŠ Jan HAKL Roman LITZMAN Jiří

  Conference abstract

  Year: 2025, type: Conference abstract

• First report from the Czech national registry of inborn errors of immunity (2012-2025)

  CHOVANCOVÁ Zita HLAVÁČKOVÁ Eva HAKL Roman MILOTA Tomas KRALICKOVA Pavlina MALKUSOVA Ivana HUTYROVA Beata SAFAROVA Michaela VYDLAKOVA Jana JILEK Dalibor NOVAK Jiri SCHNEIDEROVÁ Helena KRALOVA Petra ZIMULOVA Alena NOVAK Vitezslav BYSTRON Jaromir ZAVESKA Dita LATALOVA Vendula KOPRIVA Frantisek KASL Milan KRACIK Vladimir FORMANKOVA Renata SEDLACEK Petr VYTISKOVA Karolina SVOBODA Michal NOVAKOVA Hana LITZMAN Jiří

  Article in Periodical

  Frontiers in immunology, year: 2025, volume: 16, edition: September 2025, DOI

• Unmet needs in hereditary angioedema: an international survey of physicians

  BUTTGEREIT Thomas AULENBACHER Felix ADATIA Adil AYALA Carolina Vera AL-NESF Maryam Ali ALTRICHTER Sabine ABUZAKOUK Mohamed AL-AHMAD Mona ALI Ramzy Mohammed BERARDI Alejandro BOCCON-GIBOD Isabelle BOUILLET Laurence BRUSSINO Luisa BARESIC Marko BUSSE Paula J BETSCHEL Stephen D CHONG-NETO Herberto LLOSA Oscar Calderon CRAIG Timothy J DORR Anthony D JUNIOR Sergio Duarte Dortas FOMINA Daria FARKAS Henriette FOK Jie Shen GRUMACH Anete S GREVE Jens GUILARTE Mar GONCALO Margarida GRIVCHEVA-PANOVSKA Vesna HIDE Michihiro HAKL Roman JINDAL Ankur KATELARIS Constance H KAMALESWARAN Shailajah KINACIYAN Tamar LATYSHEVA Elena SOUSA Jose Ignacio Larco BELLFILL Ramon Lleonart MOBAYED Hassan METZ Martin NASR Iman MITREVSKA Natasa T NICOLA Stefania PARISI Claudio Alberto Salvador POREBSKI Grzegorz PETER Jonny FERRIANI Mariana Paes Leme FILHO Nelson Rosario SEKEREL Buelent Enis SERPA Faradiba Sarquis STOBIECKI Marcin TRAINOTTI Susanne VALERIEVA Anna WONGSA Chamard WONG Jane C Y YUCEL Esra LI Yinglei NENCI Chiara MAURER Marcus MAGERL Markus LI Philip H

  Article in Periodical

  Orphanet Journal of Rare Diseases, year: 2025, volume: 20, edition: 1, DOI

2024

• PLAUR alternative splicing in patients with different severity of hereditary angioedema (HAE)

  BAROŠ Jan HAKL Roman BALLONOVÁ Lucie KULÍŠKOVÁ Petra SLANINA Peter ŠTÍCHOVÁ Julie VLKOVÁ Marcela SOUČEK Přemysl FREIBERGER Tomáš LITZMAN Jiří

  Conference abstract

  Year: 2024, type: Conference abstract

• Systematická analýza genu SERPING1 odhalila v kohortě českých pacientů s HAE výrazně vyšší zastoupení sestřihových variant

  GROMBIŘÍKOVÁ Hana BÍLY Viktor SOUČEK Přemysl KRAMÁREK Michal HAKL Roman BALLONOVÁ Lucie RAVČUKOVÁ Barbora ŘÍČNÁ Dita KOŽENÁ Karolína KRATOCHVÍLOVÁ Lucie SOBOTKOVA Marta ZACHOVA Radana KUKLÍNEK Pavel KRÁLÍČKOVÁ Pavlína KRCMOVA Irena HANZLIKOVA Jana VACHOVA Martina KRYSTUFKOVA Olga DANKOVA Eva JESENAK Milos NOVACKOVA Martina SVOBODA Michal LITZMAN Jiří FREIBERGER Tomáš

  Requested lectures

  Year: 2024, type: Requested lectures

• The Chronic Angioedema Registry (CARE): Rationale, Methods and Implementation

  BUTTGEREIT T. AULENBACHER F. GUTSCHE A. KOLKHIR P. WELLER K. VERA AYALA C. MAGERL M. FARKAS H. GRUMACH A. S. AYGOEREN-PUERSUEN E. BARA N. BEN-SHOSHAN M. BERNSTEIN J. BETSCHEL S. BOUILLET L. CABALLERO T. CANCIAN M. CASTALDO A. J. CIMBOLLEK S. COHN D. M. CRAIG T. FOMINA D. GELINCIK A. GRIVCHEVA-PANOVSKA V. JINDAL A. KATELARIS C. KESSEL A. KINACIYAN T. LONGHURST H. J. MARTINEZ-SAGUER I. RIEDL M. SCHOEFFL C. STAUBACH P. ZANICHELLI A. ZHI Y. BALLE BOYSEN H. FOK J. S. LI P. H. HAKL Roman HIDE M. PETER J. MAURER M.

  Article in Periodical

  CLINICAL AND EXPERIMENTAL ALLERGY, year: 2024, volume: 54, edition: 9, DOI

• Timing of Onset of Garadacimab for Preventing Hereditary Angioedema Attacks

  STAUBACH Petra TACHDJIAN Raffi LI H. Henry HAKL Roman AYGÖREN-PÜRSÜN Emel WIEMAN Lolis JOHN-PHILIP Lawo CRAIG Timothy J.

  Article in Periodical

  Clinical & Experimental Allergy, year: 2024, volume: 54, edition: 12, DOI

2023

• An investigational oral plasma kallikrein inhibitor for on-demand treatment of hereditary angioedema: atwo-part, randomised, double-blind, placebo-controlled, crossover phase 2 trial

  AYGOEREN-PUERSUEN Emel ZANICHELLI Andrea COHN Danny M CANCIAN Mauro HAKL Roman KINACIYAN Tamar MAGERL Markus MARTINEZ-SAGUER Inmaculada STOBIECKI Marcin FARKAS Henriette KIANI-ALIKHAN Sorena GRIVCHEVA-PANOVSKA Vesna BERNSTEIN Jonathan A LI H Henry LONGHURST Hilary J AUDHYA Paul K SMITH Michael YEA Christopher M MAETZEL Andreas LEE Daniel K FEENER Edward P GOWER Richard LUMRY William R BANERJI Aleena RIEDL Marc A MAURER Marcus

  Article in Periodical

  Lancet, year: 2023, volume: 401, edition: 10375, DOI

• Myeloid lineage cells evince distinct steady-state level of certain gene groups in dependence on hereditary angioedema severity

  BALLONOVÁ Lucie SOUČEK Přemysl SLANINA Peter RÉBLOVÁ Kamila ZAPLETAL Ondřej VLKOVÁ Marcela HAKL Roman BÍLY Viktor GROMBIŘÍKOVÁ Hana SVOBODOVÁ Eliška KULÍŠKOVÁ Petra ŠTÍCHOVÁ Julie SOBOTKOVÁ Marta RADANA Zachová HANZLÍKOVÁ Jana VACHOVÁ Martina KRÁLÍČKOVÁ Pavlína KRČMOVÁ Irena JESEŇÁK Miloš FREIBERGER Tomáš

  Article in Periodical

  FRONTIERS IN GENETICS, year: 2023, volume: 14, edition: July 2023, DOI