Project information
National Institute of Virology and Bacteriology
(NIVB)
- Project Identification
- LX22NPO5103
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Robert Vácha, PhD.
- Mgr. Gabriel Demo, Ph.D.
- Mgr. Martina Drabinová
- Francesco Luca Falginella, Ph.D.
- Ing. Tibor Füzik, Ph.D.
- Mgr. Mária Gondová
- Ing. et Ing. Miroslav Haman
- Mgr. Adelheid Hanáčková
- Ing. Ondřej Kroutil, Ph.D.
- Timothée Emmanuel Jonathan Rivel, Ph.D.
- Mgr. Jana Salamonová
- prof. RNDr. Robert Vácha, PhD.
- Other MU Faculty/Unit
- Faculty of Medicine
- Other MU Faculty/Unit
-
Faculty of Science
- prof. RNDr. Roman Pantůček, Ph.D.
- Mgr. Tibor Botka, Ph.D.
- Lenka Buňatická
- prof. RNDr. Jiří Doškař, CSc.
- Mgr. Adéla Finstrlová, Ph.D.
- Mgr. Jiřina Havránková
- Mgr. Vojtěch Kovařovic, Ph.D.
- Mgr. Lucie Kuntová, Ph.D.
- Mgr. Ivana Mašlaňová, Ph.D.
- Mgr. Michal Zeman, Ph.D.
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. PhDr. Zdeněk Hostomský, CSc.
Palacký University, Olomouc
Prague Institute of Chemical Technology
Biological Centre of the ASCR, v. v. i.
Basic and oriented or clinical research on viruses and pathogenic bacteria is essential to understand the processes by which they cause disease, how they escape the immune system and how they can resist treatment. Therefore, research activities at the National Institute of Virology and Bacteriology will focus on characterizing pathogens causing existing and emerging infectious diseases, describing virus and bacteria interactions with the host, understanding the molecular mechanisms of pathogenesis, and developing antiviral and antibacterial agents and vaccines. Individual research groups will work on viruses and bacteria causing diseases with significant health and economic impact, including HIV-1, influenza, tick-borne encephalitis, hepatitis B, SARS-CoV-2, enteroviruses, and the bacteria B. pertussis, S. aureus, and T. pallidum. By working with pathogens that are relevant to current clinical practice, the research groups will have the expertise and equipment for the ongoing study of new pathogens that could become prevalent in the human population in the future.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 196
2025
-
Split Membrane: A New Model to Accelerate All-Atom MD Simulation of Phospholipid Bilayers
Journal of Chemical Information and Modeling, year: 2025, DOI
-
STEPWISE MECHANISM OF IF2 α-DRIVEN BACTERIAL TRANSLATION INITIATION
Year: 2025, type: Conference abstract
-
STRUCTURAL AND MECHANISTIC INSIGHTS INTO REPLICATION OF RIFT VALLEY FEVER VIRUS
Year: 2025, type: Conference abstract
-
Structural basis of ribosome maturation and translational recovery in E. coli lacking RimM maturation factor
Year: 2025, type: Conference abstract
-
Structural insights into ribosome anti-association mechanism in archaea
Year: 2025, type: Conference abstract
-
STRUCTURES OF ASYMME TRIC PARTICLES OF TBEV PROVIDE INSIGHT INTO FLAVIVIRUS ASSEMBLY AND MATURATION
Year: 2025, type: Conference abstract
-
Studies of microbiological quality of preparations with antimicrobial preservatives and therapeutic bacteriophages of the genera Pbunavirus and Kayvirus
Year: 2025, type: Conference abstract
-
Targeting the Rift Valley Fever Virus Polymerase: Resistance Mechanisms and Structural Insights
ACS Infectious Diseases, year: 2025, DOI
-
The pharmaceutical quality of freeze-dried tablets containing therapeutic bacteriophages against Pseudomonas aeruginosa and Staphylococcus aureus
International Journal of Pharmaceutics, year: 2025, volume: 671, edition: February, DOI
-
THE ROLE OF SEMI SEMI-DISORDERED SCAFFOLD PROTEINS IN PHAGE LUZ19 PROCAPSID ASSEMBLY
Year: 2025, type: Conference abstract