Bezpečná biotechnologie alotransplatovaných hematopoetických kmenových buněk u vybraných solidních a hematologických nádorů jako adoptivní imunoterapie (NPVII11001)

Project Identification
Project Period
7/2006 - 6/2011
Investor / Pogramme / Project type
Ministry of Education, Youth and Sports of the CR
MU Faculty or unit
Faculty of Medicine
Cooperating Organization
Genex CZ, s.r.o.

Safe biotechnology of allotransplated hematopoietic stem cells in selected solid and haematologic tumors as an adoptive immunotherapy

The project focuses on the adoptive immunotherapy using experimental allogeneic hematopoietic stem cell transplantation. It primarily concentrates on finding a safe biotechnology of allogeneic stem cell graft preparation to minimize its unwanted alloreactivity leading often to lethal graft-versus-host reaction, and at the same time to preserve and potentiate its anti-tumor reactivity. Experimental verification of this procedure could lead to a rapid progress in the clinical usage of allogeneic transplantation in oncology and other fields.



Total number of publications: 82

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