Project information
iNEXT - Infrastructure for NMR, EM and X-ray crystallography for translational research (iNEXT)

Information

This project doesn't include Faculty of Medicine. It includes Central European Institute of Technology. Official project website can be found on muni.cz.

Project Identification

653706

Project Period

9/2015 - 8/2019

Investor / Pogramme / Project type

European Union

Horizon 2020
RI Research Infrastructures (Excellent Science)

MU Faculty or unit

Central European Institute of Technology

prof. RNDr. Vladimír Sklenář, DrSc.

Cooperating Organization

Universiteit Utrecht

Responsible person Prof. Rolf Boelens

The iNEXT (infrastructures for NMR, EM and X-ray crystallography for translational research) partnership aims to provide the full range of infrastructures necessary to translate technical excellence and scientific leadership of Structural Biology in Europe to impact modern biomedicine. It will facilitate the development of innovative drugs and biologicals, to meet the major challenges we will face in human and animal health.

Publications

Total number of publications: 9

2023

Structural basis for different membrane-binding properties of<i> E.</i><i> coli</i> anaerobic and human mitochondrial 8-oxidation trifunctional enzymes

SAH-TELI Shiv K PINKAS Matyáš HYNONEN Mikko J BUTCHER Sarah J WIERENGA Rik K NOVÁČEK Jiří VENKATESAN Rajaram

Article in Periodical

Structure, year: 2023, volume: 31, edition: 7, DOI

2022

Human myelin proteolipid protein structure and lipid bilayer stacking

RUSKAMO Salla RAASAKKA Arne PEDERSEN Jan Skov MARTEL Anne ŠKUBNÍK Karel DARWISH Tamim PORCAR Lionel KURSULA Petri

Article in Periodical

Cellular and molecular life sciences, year: 2022, volume: 79, edition: 8, DOI

2019

In Cell NMR Spectroscopy: Investigation of G-Quadruplex Structures Inside Living Xenopus laevis Oocytes

KRAFČÍKOVÁ Michaela HANSEL-HERTSCH R. TRANTÍREK Lukáš TRANTÍRKOVÁ Silvie

Article in Periodical

G-QUADRUPLEX NUCLEIC ACIDS: METHODS AND PROTOCOLS, year: 2019, volume: 2035, edition: 2019, DOI
In-Cell NMR Spectroscopy of Nucleic Acids in Human Cells

VÍŠKOVÁ Pavlína KRAFČÍK Daniel TRANTÍREK Lukáš TRANTÍRKOVÁ Silvie

Article in Periodical

Current Protocols in Nucleic Acid Chemistry, year: 2019, volume: 76, edition: 1, DOI
Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy

KRAFČÍKOVÁ Michaela DŽATKO Šimon CARON C. GRANZHAN A. FIALA Radovan LOJA Tomáš TEULADE-FICHOU M.P. FESSL T. HANSEL-HERTSCH R. MERGNY J.L. FOLDYNOVA-TRANTIRKOVA S. TRANTÍREK Lukáš

Article in Periodical

Journal of the American Chemical Society, year: 2019, volume: 141, edition: 34, DOI

2018

Advances in the cellular structural biology of nucleic acids

GIASSA Ilektra-Chara RYNEŠ Jan FESSL T. TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

Article in Periodical

FEBS LETTERS, year: 2018, volume: 592, edition: 12, DOI
Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells

DŽATKO Šimon KRAFČÍKOVÁ Michaela HANSEL-HERTSCH R. FESSL T. FIALA Radovan LOJA Tomáš KRAFČÍK Daniel MERGNY J.L. TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

Article in Periodical

Angewandte Chemie International Edition, year: 2018, volume: 57, edition: 8, DOI
Multivalency regulates activity in an intrinsically disordered transcription factor

CLARK S. MYERS J.B. KING A. FIALA Radovan NOVÁČEK Jiří PEARCE G. HEIERHORST J. REICHOW S.L. BARBAR E.J.

Article in Periodical

elife, year: 2018, volume: 7, edition: MAY, DOI
NMR spectroscopy of nucleic acids in human cells

TRANTÍREK Lukáš

Conference abstract

Year: 2018, type: Conference abstract