Project information
Complex estimation of relation of MMP-1,2,3,9,TIMP-1 and ACE polymorphisms to left ventricuzlar remodelation and to medium-term prognosis after acute infarct myocardum with ST elevation treated by primary PCI

Project Identification

NR9356

Project Period

1/2007 - 12/2009

Investor / Pogramme / Project type

Ministry of Health of the CR

Ministry of Agriculture R&D Programme

MU Faculty or unit

Faculty of Medicine

Keywords

acute infarct myocardum, gene, polymorphism, serum levels

Cooperating Organization

University Hospital Brno-Bohunice

Responsible person MUDr. Martin Poloczek
Responsible person MUDr. Otakar Boček
Responsible person MUDr. Petr Jeřábek
Responsible person MUDr. Petr Neugebauer, Ph.D.
Responsible person prof. MUDr. Mgr. Jiří Pařenica, Ph.D.

Assesment of genetic variability of MMP, TIMP and ACE genes in respect in respect to acute infarct myocardum and its intermediate phenotype, inclusive of the analysis of selected serum levels.

Publications

Total number of publications: 8

2011

Difference in angiotensinogen haplotype frequences between chronic heart failure and advanced atherosclerosis patients - new prognostic factor?

PÁVKOVÁ GOLDBERGOVÁ Monika ŠPINAROVÁ Lenka ŠPINAR Jindřich PAŘENICA Jiří ŠIŠKOVÁ Lenka GROCH Ladislav MÁCHAL Jan VAŠKŮ Anna

Article in Periodical

Physiological Research, year: 2011, volume: 60, edition: 1
Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males

PAŘENICA Jiří KALA Petr JARKOVSKÝ Jiří POLOCZEK Martin BOČEK Otakar JEŘÁBEK Petr NEUGEBAUER Petr VYTISKA Miroslav PARENICOVA Ilona TOMCIKOVA D. PÁVKOVÁ GOLDBERGOVÁ Monika ŠPINAR Jindřich

Article in Periodical

Physiological Research, year: 2011, volume: 60, edition: 1

2010

RXRA introne polymorphism and ABO blood groups in chronic heart failure

PÁVKOVÁ GOLDBERGOVÁ Monika ŠPINAROVÁ Lenka ŠPINAR Jindřich VÍTOVEC Jiří PAŘENICA Jiří POLOCZEK Martin VAŠKŮ Anna

Article in Periodical

Cent. Eur. J. Biol, year: 2010, volume: 6, edition: 5

2009

Association of TIMP-2 intron polymorphism with LV systolic dysfunction in acute MI

PÁVKOVÁ GOLDBERGOVÁ Monika PAŘENICA Jiří KALA Petr POLOCZEK Martin ŠPINAR Jindřich LAUŠOVÁ Jarmila VAŠKŮ Anna

Conference abstract

Year: 2009, type: Conference abstract
Assocition of the ACE gene I/D polymorphism and left myocardial systolic dysfunction in patients with acute ST elevations myocardial infarction treated by primary PCI

PÁVKOVÁ GOLDBERGOVÁ Monika PAŘENICA Jiří KALA Petr POLOCZEK Martin MAŇOUSEK Jan TESÁK Martin ŠPINAR Jindřich VAŠKŮ Anna

Conference abstract

Year: 2009, type: Conference abstract
Matrix metalloproteinase-2 and oxidative stress in patients with STEMI treated by primary PCI

PAŘENICA Jiří PÁVKOVÁ GOLDBERGOVÁ Monika KALA Petr POLOCZEK Martin MAŇOUSEK Jan ČERMÁKOVÁ Zdena TOMAN Ondřej TOMČÍKOVÁ Daniela ŠPINAR Jindřich

Conference abstract

Year: 2009, type: Conference abstract

2008

HAPLOTYPE OF FOUR MMP2 GENE PROMOTER POLYMORPHISMS AS PROTECTION VARIANT FOR ISCHEMIC HEART DISEASE AHEAD OF PROGRESSION TO HEART FAILURE

PÁVKOVÁ GOLDBERGOVÁ Monika POLOCZEK Martin PAŘENICA Jiří ŠPINAROVÁ Lenka GROCH Ladislav ŠPINAR Jindřich VAŠKŮ Anna

Conference abstract

Year: 2008, type: Conference abstract
Protection Variant of MMP2 Polymorphism Haplotype - A New Prognostic Factor for Ischemic Heart Disease Ahead of Progression to Heart Failure?

PÁVKOVÁ GOLDBERGOVÁ Monika PAŘENICA Jiří ŠPINAR Jindřich POLOCZEK Martin ŠPINAROVÁ Lenka GROCH Ladislav VAŠKŮ Anna

Conference abstract

Year: 2008, type: Conference abstract