Project information
Phenotype dynamics in patient treated by paroxetine regarding the clinical correlates
- Project Identification
- NF6159
- Project Period
- 1/2000 - 1/2002
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- R&D of Neurology and Psychiatry
- MU Faculty or unit
- Faculty of Medicine
The aim of the project is to establish the role of CYP 2D6 genetic polymorphism with to the efficacy and drug safety of treatment of anxiety disorders with paroxetine and duration of metabolic phenotype conversion within treatment discontinuation.
Publications
Total number of publications: 15
2003
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Účinnost a snášenlivost léčby úzkostných poruch paroxetinem a alprazolamem
Psychiatrie pro praxi, year: 2003, volume: 4, edition: 6
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Výběr antidepresivní léčby z hlediska interakčního potenciálu a výskytu sexuálních dysfunkcí
Psychiatrie, year: 2003, volume: 7, edition: suppl.1
2002
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Acetylační polymorfismus a psychiatrická onemocnění
Klinická farmakologie a farmacie, year: 2002, volume: 16, edition: 1-2
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CYP2D6 and paroxetine treatment of depressive disorder
18th European Workshop on Drug Metabolism, Abstract Book, year: 2002
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Fenotypická konverze CYP 2D6 a sexuální dysfunkce
Klinická farmakologie a farmacie, year: 2002, volume: 16, edition: 1-2
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Klinický význam CYP 2D6 v průběhu léčby novějšími antidepresivy
Česká a slovenská psychiatrie, year: 2002, volume: 98, edition: 5
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Monitorování sexuálních funkcí za užití škál UKU,ASEX,SFM/SFŽ
Year: 2002, number of pages: 1 s.
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Relation between sexual dysfunctions and CYP 2D6 activity
European psychiatry, year: 2002, volume: 17, edition: Suppl. 1
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Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment
Journal of Sex and Marital Therapy, year: 2002, volume: 28, edition: 5
2001
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Dynamics of clinical response to paroxetine in coherence with CYP 2D6 metabolic status during long-term therapy of depressive disorder
International Congress 2001: "Severe Debilitating diseases". Abstract Book., year: 2001