Dynamics of proteins interacting with Dishevelled and their importance for Wnt signalling
- Project Identification
- Project Period
- 1/2009 - 12/2013
- Investor / Pogramme / Project type
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Science
- Wnt, Dishevelled, dynamics, tandem affinity purification
- Cooperating Organization
University of South Bohemia České Budějovice
- Responsible person Mgr. Lukáš Trantírek, Ph.D.
Total number of publications: 15
Fibroblast growth factor and canonical WNT/beta-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage
Biochimica et Biophysica Acta - Molecular Basis of Disease, year: 2015, volume: 1852, edition: 5, DOI
beta-Arrestin Interacts with the Beta/Gamma Subunits of Trimeric G-Proteins and Dishevelled in the Wnt/Ca2+ Pathway in Xenopus Gastrulation
PLOS ONE, year: 2014, volume: 9, edition: 1, DOI
beta-Arrestin Promotes Wnt-induced Low Density Lipoprotein Receptor-related Protein 6 (Lrp6) Phosphorylation via Increased Membrane Recruitment of Amer1 Protein
Journal of Biological Chemistry, year: 2014, volume: 289, edition: 2, DOI
Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6
FASEB JOURNAL, year: 2014, volume: 28, edition: 5, DOI
Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1 epsilon and Frizzled5
Journal of Biological Chemistry, year: 2014, volume: 289, edition: 34, DOI
Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the wnt signaling pathway.
Science Signaling, year: 2014, volume: 7, edition: 317, DOI
The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling.
PLoS Biology, year: 2013, volume: 2013, edition: 11(5), DOI
Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons.
Molecular and cellular biology, year: 2013, volume: 33, edition: 1, DOI
Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells.
Proceedings of the National Academy of Sciences of the United States of America, year: 2013, volume: 110, edition: 7, DOI
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P(2) to LRP6 phosphorylation.
The EMBO journal, year: 2011, volume: 30, edition: 8, DOI