Project information
Expression of integrins during differentiation of Schwann cells and derivative structures of the peripheral nervous system of the rat
- Project Identification
- GA309/97/0107
- Project Period
- 1/1997 - 1/1999
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
Extracellular matrix (ECM) of Schwann cells (Sc) and derived auxiliary structures plays an important role during regeneration in peripheral nervous system (PNS). Integrins involved in interactions between the cell and ECM have probably crucial function i n transition of morphogenic information from the ECM during differentiation of Sc and derived structures. During maturation the Sc take various shapes and assemble the basal lamina on the surface. The goal of present project is determination of: i/ inte
Publications
Total number of publications: 14
2001
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Laminin molecules in freeze-treated nerve segments are associated with migrating Schwann cells that display the corresponding a61 integrin receptor
Glia, year: 2001, volume: 33, edition: 1
2000
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Are resident laminin molecules of the extracellular matrix needed for Schwann cell migration?
The Histochemical Journal, year: 2000, volume: 2000, edition: 32
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Expression of integrin chains for laminin in the Schwann cells migrating into the freeze-injured dorsal root ganglia of the rat - an immunohistochemical study
The Histochemical Journal, year: 2000, volume: 2000, edition: 32
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Migrating Schwann cells support the endoneurium of freeze-treated nerve segment by laminins, fibronectin, thrombospondin, and chondroitin sulfate.
Sborník lékařský, year: 2000
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Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation
Anatomy and Embryology, year: 2000, volume: 202, edition: 3
1999
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Acellular Nerve Segments and Migration of Schwann Cells
Scripta Medica, year: 1999, volume: 72, edition: 5-6
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Immunohistochemical localization of laminin-1 in the acellular nerve grafts is associated with migrating Schwann cells which display corresponding integrin receptors
The Histochemical Journal, year: 1999, volume: 31, edition: 2
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Immunohistochemical localization of some extracellular molecules and their integrin receptors in the rat Pacinian corpuscles
The Histochemical Journal, year: 1999, volume: 31, edition: 2
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Immunohistochemical localization of some extracellular molecules and their integrin receptors in the rat Pacinian corpuscles
General Physiology and Biophysics, year: 1999, volume: 18, edition: 1
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Migration of Schwann cells and regeneration of peripheral nerves
E. J. Pathol. Histol., year: 1999, volume: 5, edition: 2