Subcortical nuclei and cortical functions – insight from the deep brain stimulation perspective (DBS3D)


This project doesn't include Faculty of Medicine. It includes Central European Institute of Technology. Official project website can be found on

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Project Identification
Project Period
1/2021 - 12/2023
Investor / Pogramme / Project type
Czech Science Foundation
MU Faculty or unit
Central European Institute of Technology
Cooperating Organization
Institute of Scientific Instruments of the ASCR, v. v. i.

The main aim of the project is to study cortico-subcortical interactions via advanced analysis of electrophysiological phenomena from microrecording to the whole brain levels. These interactions are basis for the understanding of the brain’s functioning, particularly in its pathological alterations; To investigate brain electrical activity in diseases involving both cortical and subcortical structures, i.e. with primarily subcortical pathology (Parkinson’s Disease) and primarily cortical pathology (Epilepsy). To identify electrophysiological phenomena related to DBS therapy with the main focus on possible predictive biomarkers. To follow up our pilot data defining optimal and suboptimal response to DBS in a long-term neuropsychological observation.


Total number of publications: 7

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