Arrhythmogenic potential of TP-1 in animal model
- Project Identification
- Project Period
- 1/2021 - 12/2021
- Investor / Pogramme / Project type
- Masaryk University
- MU Faculty or unit
- Faculty of Medicine
The project introduces anesthetised guinea pig as a model for arrhythmogeneicity testing of TP-1, new drug with potential beta adrenergic action. As whole body model, it allows to evaluate complex reaction of cardiovascular system to tested drug. From ECG, RR intervals, corrected QT intervals and incidence of ventricular arrhythmias will be evaluated. Implementation of this model will significantly enhance existing methodological approaches in the Laboratory of Experimental Cardiology.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Total number of publications: 6