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Project information
Arrhythmogenic potential of TP-1 in animal model

Project Identification
MUNI/IGA/1098/2020
Project Period
1/2021 - 12/2021
Investor / Pogramme / Project type
Masaryk University
  • Internal grant agency MU
MU Faculty or unit
Faculty of Medicine

The project introduces anesthetised guinea pig as a model for arrhythmogeneicity testing of TP-1, new drug with potential beta adrenergic action. As whole body model, it allows to evaluate complex reaction of cardiovascular system to tested drug. From ECG, RR intervals, corrected QT intervals and incidence of ventricular arrhythmias will be evaluated. Implementation of this model will significantly enhance existing methodological approaches in the Laboratory of Experimental Cardiology.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Sustainable Development Goal No. 3 – Good health and well-being Sustainable Development Goal No. 17 – Partnerships for the goals

Publications

Total number of publications: 6

2022

2021

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