Project information
Classification of brain tumors using advanced techniques of multimodal diffusion MRI data
- Project Identification
- NU21-08-00359
- Project Period
- 5/2021 - 12/2024
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- Ministry of Health Research Programme 2020 - 2026
- Subprogram 1 - standard
- MU Faculty or unit
- Faculty of Informatics
- Cooperating Organization
-
University Hospital Brno-Bohunice
- Responsible person doc. MUDr. Miloš Keřkovský, Ph.D.
Brain tumours comprise a relatively rare disease, but one that is a significant cause of morbidity and mortality. Diagnosis of brain tumours, which is based mainly on magnetic resonance imaging (MRI), is crucial for choosing optimal treatment strategies. In many cases, however, MRI provides non-specific findings and differentiation of individual types of tumours may be problematic using conventional MRI methods. In recent years, various MRI diffusion imaging techniques have been introduced that, in conjunction with advanced data analysis, have the potential to upgrade the possibilities for non-invasive classification of brain tumours. The main goal of this project will be to develop automated methodological procedures enabling the differentiation of individual types of brain tumours based on multimodal MRI data. The prospective study will include about 240 patients with brain tumours who will undergo MRI of the brain and subsequent resection or stereotactic biopsy of the pathological brain lesion. The MRI protocol will include diffusion tensor imaging (DTI) and intra-voxel incoherent motion (IVIM) techniques. Using machine-learning methods, automated techniques of MRI images segmentation will be developed together with advanced classification algorithms enabling differentiation of individual tumour types based on their morphological and diffusion features. The accuracy of the stated procedures in the matter of differentiating individual types of tumours will be verified in correlation with histopathological findings.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 3
2023
-
Can intravoxel incoherent motion MRI predict meningioma consistency?
Year: 2023, type: Conference abstract
2022
-
Differentiation of high grade glioma and brain metastasis using intravoxel incoherent motion MRI
Year: 2022, type: Appeared in Conference without Proceedings
-
Federated learning enables big data for rare cancer boundary detection
Nature Communications, year: 2022, volume: 13, edition: 7346, DOI