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Project information
The impact of derivation substrate on differentiation of human embryonic stem cells for the cell therapy

Project Identification
MUNI/IGA/1332/2021
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
  • Internal grant agency MU
MU Faculty or unit
Faculty of Medicine

Human embryonic stem cells (hESC) are able to differentiate into every cell type in the human body (e.g., neural, cardiac, or retinal cells), which may then be the basis for cell therapies. Our aim is to examine how substrate used for derivation of hESC influences their differentiation propensity, which is critical for the potential application of hESC in a clinical setting. Here, we study the capacity of hESC derived on different substrates to produce cells of all three embryonal lineages.

Publications

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