National institute for cancer research (NÚVR)
- Project Identification
- LX22NPO5102
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
- Faculty of Medicine
- Other MU Faculty/Unit
- Faculty of Science
- Other MU Faculty/Unit
- Central European Institute of Technology
- Keywords
- oncology, cancer, national institute
- Cooperating Organization
-
Charles University
- Responsible person prof. MUDr. Alexi Šedo, DrSc.
The aim of the project is to create a nationwide network of collaborating workplaces conducting cutting-edge research in the field of oncology, which will take the form of a "National Institute". The reason for the creation of this authority is that research in oncology is currently not coordinated in any way and is fragmented across institutions.
The establishment of a National Institute for Cancer Research will bring together cutting-edge scientific expertise, tertiary education and relevant medical/health information resources. The thematic complementarity of the individual departments within the National Cancer Research Institute will allow for a comprehensive approach necessary for modern cancer research, concentrating on priority areas of medical education and research in the Czech Republic. Cancer research will thus become much more coordinated, strategic and efficient.
The great advantage of the National Institute is its transformative character, i.e. no new infrastructure will be built (an exception is the necessary construction of the GMP for somatic cell and gene therapy ATMP in pavilion C03), but the development and modernisation of existing capacities and human resources. This approach is highly efficient and financially sustainable in the long term.
The network of collaborating sites will consist of three Nodes (Prague Node - coordinator, Brno Node, Olomouc Node), which will cover the whole Czech Republic. The individual Nodes will be connected through a consortium agreement that defines the frameworks and rules of cooperation.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 2
2022
-
New-Generation Heterocyclic Bis-Pentamethinium Salts as Potential Cytostatic Drugs with Dual IL-6R and Mitochondria-Targeting Activity
Pharmaceutics, year: 2022, volume: 14, edition: 8, DOI
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Pentamethinium salts suppress key metastatic processes by regulating mitochondrial function and inhibiting dihydroorotate dehydrogenase respiration
Biomedicine & Pharmacotherapy, year: 2022, volume: 1254, edition: October 2022, DOI