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On July 15, 2026, the Czech Ministry of Health presented the first National Strategy for Clinical Trials of Human Medicinal Products in the Czech Republic 2035, which establishes a long-term framework for the development of clinical research, the improvement of conditions for conducting clinical trials, and the expansion of patient access to innovative treatments. The national research infrastructure CZECRIN also contributed to the preparation of the document.
Through CZECRIN, representatives of the Faculty of Medicine were part of a working group bringing together representatives of the Ministry of Health, the State Institute for Drug Control, professional societies, healthcare providers, patient organisations, and other partners active in the field of clinical research.
Regina Demlová, director of CZECRIN—who also serves as head of the Institute of Pharmacology and director of the CREATIC Center of Excellence at our faculty—spoke during the presentation of the strategy. She highlighted the importance of academic clinical trials, the number of which in the Czech Republic has not yet reached the level of domestic research institutions' potential. According to her, the new strategy represents an important step toward systematically supporting academic research, developing professional capacities, and strengthening international cooperation among Czech research centers.
The strategy’s main priorities include further digitisation of processes, standardisation of contractual procedures, support for academic clinical trials, development of professional capacities, and more intensive communication with both patients and the professional community. One of the first concrete outcomes will be the launch of a new national web portal on clinical trials, which CZECRIN is also helping to develop. The portal will offer verified and clearly organised information in one place for patients, healthcare professionals, researchers, and clinical trial sponsors. Its launch is planned for the summer of 2026.
The National Strategy for Clinical Trials of Human Medicinal Products in the Czech Republic 2035 is available here.
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What happens when a patient does not have access to sufficiently effective or appropriate treatment? Under precisely defined conditions, a hospital exemption may allow access to an unapproved advanced therapy medicinal product. This can offer patients with rare or serious diseases a treatment option that would otherwise be unavailable to them. The first hospital exemption in the Czech Republic was granted to the CREATIC Center of Excellence at the Faculty of Medicine for dendritic cell-based anticancer immunotherapy.