Jak nejlépe blokovat renin-angiotenzinový systém u nemocných s hypertenzí a diabetes mellitus?
| Title in English | The best method of renin-angiotensin-aldosterone system blockade in patients with hypertension and diabetes mellitus? |
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| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Kardiologická revue - Interní medicína |
| MU Faculty or unit | |
| Citation | |
| Field | Other specializations of internal medicine |
| Keywords | diabetes mellitus type 2; hypertension; renin-angiotensin-aldosterone system |
| Description | The aim of this article is to evaluate the efficacy and safety of different methods of blockade of the renin-angiotensin-aldosterone system (RAAS) in patients with type 2 diabetes. It is not entirely clear how to best and most eff ectively block the RAAS system in diabetic patients due to the lack of data from randomised clinical trials. Knowledge about treatment methods in this group of patients is obtained only from subgroup analyses and metaanalyses, where results maybe less reliable. Combination therapy with ACE inhibitors and ARBs could more eff ectively block the RAAS, but present fi ndings demonstrate confl icting results, particularly as regards the safety of patients. |