Pacient si stěžuje na bolesti v páteři nebo na únavu a slabost. Jak rozeznám, zda je příčinou spondylartróza, věk nemocného anebo mnohočetný myelom?
| Title in English | The patient complains of spinal pain or fatigue and weakness. How do I recognize whether their cause is spondylarthrosis, the patient’s age or multiple myeloma? |
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| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | monoclonal gammapathy of undetermined significance; multiple myeloma; osteolysis; renal failure |
| Description | Multiple myeloma has varied manifestations which resemble common patient complaints and that is why this disease is typically not diagnosed until it reaches an advanced stage. Spinal pains can be an expression of deformative and discogenous changes, but also a symptom of multiple myeloma. Pains in the long bones may result from the pain radiating from an arthrotic joint, but also from a large myelomatic osteolytic lesion which makes the bone prone to a spontaneous fracture. Pathological weariness may have many causes, multiple myeloma being one of them. Anemia may have a large number of causes and multiple myeloma is one of them. Raised creatinine levels and renal failure can also be due to many causes and again, multiple myeloma is one of them. Weakened immunity and frequent infections can also have many causes, among them multiple myeloma. Confusion and sleepiness may be due to psychiatric diagnosis, but also may result from hypercalcemia associated with multiple myeloma. |