Polyfarmakoterapie nahlížená nejen prismatem multimorbidity, ale jako další geriatrický syndrom

Title in English Polypharmacy viewed not only through the prism of multi-morbidity, but also as a independent geriatric syndrome


Year of publication 2016
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Field Other specializations of internal medicine
Keywords Old age; geriatrisation of medicine; multi-morbidity; polypharmacy; prescription; randomized clinical trials; evidence based medicine
Description Polypharmacy is common in the elderly, especially in the late age (over 75 years). Usually it is closely related to the geriatric multi-morbidity. The authors highlight the medication used in the anticipated positive and potential negative potential. While physicians often must make difficult trade-offs between the guidelines on one hand and complicated multiple morbidity, on the other hand, while trying to avoid polypharmacy (5 or more drugs), especially excessive polypharmacy (10 or more drugs). Multimorbid elderly patients who are treated in accordance with guidelines typically use large amounts of medicaments. This polypharmacy increases the risk of adverse drug reactions and drug interactions. The authors point out the pitfalls of performance of large clinical studies and EBM on one side and the daily clinical practice at the risk of their indiscriminate application, albeit with good intentions to improve the health of seniors.

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