Role hypertermické intraperitoneální chemoterapie v léčbě pokročilého a recidivujícího ovariálního karcinomu

Title in English The role of hyperthermic intraperitoneal chemotherapy in the treatment of advanced and recurrent ovarian cancer


Year of publication 2017
Type Article in Periodical
Magazine / Source Onkologie
MU Faculty or unit

Faculty of Medicine

Field Oncology and hematology
Keywords ovarian cancer; HIPEC
Description Ovarian cancer is the most common cause of death in gynaecological malignancies. The disease is diagnosed in advanced stage with peritoneal carcinomatosis in most cases. The treatment is based on primary cytoreductive surgery followed by chemotherapy. Benefit of intraperitoneal chemotherapy in frontline treatment has been confirmed. Currently, the increasing interest in potential benefit of radical cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC) in frontline ovarian cancer treatment and therapy of recurrencies is noted. The results of recent trials are limited and heterogenous. Results of ongoing phase III prospective trials are expected.

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