Serózní tubární intraepiteliální karcinomy (STIC)

Title in English Serous tuba) intraepithelial carcinoma (STIC)


Year of publication 2017
Type Article in Periodical
Magazine / Source Onkologie
MU Faculty or unit

Faculty of Medicine

Field Oncology and hematology
Keywords high grade serous carcinoma (HGSC); serous tubal intraepithelial carcinoma (STIC); BRCA; STIL; TILT; SCOUT; SEE-FIM
Description High-grade serous carcinomas (HGSC) are group of ovarial, tubal and peritoneal tumors arising from precursor lession most likely from distal part of the fallopian tube. At the time of diagnosis of HGSC are women affected with metastatic sprej of the tumor into abdominal cavity with 5 year survival of 10-30%. Among women with increased risk of HGSC (the most with BRCA mutation) witch underwent bilateral salpingo-oophorectomy is 4-17% diagnosed with STIC (serous tubal intraepithelial carcinoma) or with invasive neoplasia a aproximately 80% those tumors are found in ampular part of the fallopian tube.

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