Medical cannabis in the treatment of cancer pain and spastic conditions and options of drug delivery in clinical practice

Authors

LANDA Leoš JUŘICA Jan SLIVA Jiri PECHACKOVA Monika DEMLOVÁ Regina

Year of publication 2018
Type Article in Periodical
Magazine / Source Biomedical Papers, Olomouc: Palacky University
MU Faculty or unit

Faculty of Medicine

Citation
Web https://biomed.papers.upol.cz/artkey/bio-201801-0003_Medical_cannabis_in_the_treatment_of_cancer_pain_and_spastic_conditions_and_options_of_drug_delivery_in_clinica.php
Doi http://dx.doi.org/10.5507/bp.2018.007
Keywords cannabis; pain; cancer; spasms; multiple sclerosis; mechanism of action; THC; cannabinoids
Description The use of cannabis for medical purposes has been recently legalised in many countries including the Czech Republic. As a result, there is increased interest on the part of physicians and patients in many aspects of its application. This mini review briefly covers the main active substances of the cannabis plant and mechanisms of action. It focuses on two conditions, cancer pain and spasticity in multiple sclerosis, where its effects are well-documented. A comprehensive overview of a few cannabis-based products and the basic pharmacokinetics of marijuana's constituents follows. The review concludes with an outline for preparing cannabis (dried inflorescence) containing drug dosage forms that can be produced in a hospital pharmacy.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info