The optimal bowel preparation intervals before colonoscopy: A randomized study comparing polyethylene glycol and low-volume solutions
| Authors | |
|---|---|
| Year of publication | 2018 |
| Type | Article in Periodical |
| Magazine / Source | DIGESTIVE AND LIVER DISEASE |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1016/j.dld.2017.10.010 |
| Keywords | Ascorbic acid; Bowel preparation; Colonoscopy; Polyethylene glycol; Sodium picosulfate |
| Description | Background & aims: The optimal duration of bowel preparation has only been assessed for polyethylene glycol (PEG). The aim of the study was to determine the intervals for achieving a satisfactory quality/tolerability of the preparation using PEG/ascorbic acid (PEGA) and sodium picosulphate/magnesium citrate (SPMC), and to compare them with 4L of PEG. Methods: A randomized, endoscopist-blinded, multicentre study. The 612 outpatients referred to a colonoscopy, were prepared using PEG, SPMC, PEGA. The quality, tolerability, duration of the preparation, and the interval from the end of the preparation to the colonoscopy was assessed. Results: Optimum duration of the preparation was similar for both PEG and SPMC (>= 7.3 vs. >= 8.8 h, overall >= 8.4 h). Optimum interval to the colonoscopy was <= 11.8 h and did not differ between preparations (PEG, PEGA <= 11.8, SPMC <= 13.3 h). These times were the only predictors for a satisfactory preparation. The tolerability depends on the product type (SPMC) only. Timing of the preparation or the other factors had no impact on tolerability. Conclusion: The optimum intervals for bowel preparation are identical for all preparations. Satisfactory preparation is achived at the preparation length >= 8.4 h and the time to colonoscopy <= 11.8 h. |