Studie COLCOT

Title in English COLCOT study
Authors

ŠPINAROVÁ Lenka ŠPINAR Jindřich VÍTOVEC Jiří

Year of publication 2020
Type Article in Periodical
Magazine / Source Remedia
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.remedia.cz/Archiv-rocniku/Rocnik-2020/2-202/e-2T2-2V9.magissue.aspx
Keywords myocardial infarction; anti-inflammatory treatment; atherosclerotics events; colchicin
Description COLCOT study evaluated the administration of colchicin com pared with placebo in patients after myocardial infarction. Primary composite endpoint was the time to cardiovascular death, cardiac arrest,myocardial infarction, stroke or urgent hospitalisation for angina pectoris resulting in revascularization. treated patients reached this endpoint in 5.5% compared with placebo patients 7.1%(p 0.02).The occurence of adverse events was low and comparable with placebo, including diarrhea.

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