Primární non-Hodgkinův B-lymfom centrálního nervového systému

Title in English The primary Non-Hodgkin's central nervous system lymphoma


Year of publication 2020
Type Article in Periodical
Magazine / Source Ceska a slovenska neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Keywords primary Non-Hodgkin’s lymphoma; central nervous system
Description One of the most common proven primary CNS lymphomas is non-Hodgkin's lymphoma (NHL), which typically manifests as focal neurological and neuropsychiatric symptoms. Its incidence in the population, especially in developed countries, is rising slightly. In 2010, it was reported to be about 1-2% of all primary CNS tumors. It is currently estimated that it currently occurs in about 4–5% of primary CNS tumors, with the most common subtype in adults being diffuse large B-cell lymphoma (DLBCL) with an incidence of about 25–40% [1 , 2]. The MR of the brain plays an irreplaceable place in the diagnostic process. On MR examination, a diffuse lesion or multiple hypointensive lesions in a T2-weighted image in cerebral hemispheres are typically dominant in the basal ganglia, often with perifocal edema [3,4]. Ependymal lesions and lesions in the corpus cal losum are also described. NHL is more common in men and its prevalence increases with age in virtually all subtypes.

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