Vymizení nefrotického syndromu a zlepšení funkce ledvin u nemocné s light chain deposition disease po vysokodávkované chemoterapii s autologní transplantací kmenových krvetvorných buněk. Popis případu a přehled literatury

Title in English Complete remission of nephrotic syndrome and improvement of renal function in a patient with light chain deposition disease following high dose chemotherapy with transplantation of autologous haematopoietic stem cells. A case study and review of literatu
Authors

ADAM Zdeněk KREJČÍ Marta POUR Luděk ŠTĚPÁNKOVÁ Soňa ČERMÁKOVÁ Z. VOSKA L. TEPLAN V. KŘIVANOVÁ Andrea HÁJEK Roman MAYER Jiří

Year of publication 2009
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords Light chain deposition disease; multiple myeloma
Description We draw the reader's attention to the possibility of nephrotoxic effects of high dose melphalan (post conditioning renal insufficiency) in patients with nephrotic syndrome caused by light chain deposits as AL-amyloid or amorphous light chains deposits (LCDD)and we document the importance of plasma free light chain detection.
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