Renal denervation in the treatment of resistant arterial hypertension and other perspectives

Authors

POLOCZEK Martin VYSOČANOVÁ Petra MIKLÍK Roman NYKL Igor KALA Petr

Year of publication 2012
Type Article in Periodical
Magazine / Source Cor et Vasa
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords Renal denervation; Resistant hypertension; Sympathetic nervous system
Description Renal denervation (RDN) is a new perspective method for the treatment of resistant hypertension. Surgical sympathectomy has been considered as a possible treatment of hypertension for many years - long before the discovery of antihypertensive drugs. The selective percutaneous transcatheter application of radiofrequency energy in renal arteries to eliminate sympathetic nerve fibres has been used in human medicine since 2009. The recent boom of this method has been supported by published clinical studies showing efficacy of this new treatment modality. Nevertheless, RDN is still an experimental method to be used only in specialized research centers. In this review we will provide up-to-date information about the use of RDN as a novel method for the treatment of hypertension as well as discuss potential perspectives of RDN in the treatment of various medical conditions.

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