Výsledky přežívání pacientů s osteosarkomem před 30 lety a nyní
| Title in English | SURVIVAL RATES IN OSTEOSARCOMA PATIENTS 30 YEARS AGO AND AT PRESENT |
|---|---|
| Authors | |
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Ortopedie |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | osteosarcoma; survival |
| Description | Introduction: Survival rates in osteosarcoma patients 30 years ago and at present. Background: The objective of this study was to compare the survival results of patients with osteosarcoma 30 years ago and at present. Methods and material: The authors compared two groups of osteosarcoma patients from the same orthopaedic department treated in the years 2000-2005 and 1980-1985. All patients admitted to the clinic in the aforementioned years with the diagnosis of osteosarcoma were included in the two groups and the results were evaluated five years after treatment. Results: In both groups, the incidence of osteosarcoma most often falls in the second and third decades, the most frequent osteosarcoma localisation being the area of the knee joint. The amputation rate in the 1980-1985 Group was 39% and 26% in the 2000-2005 Group. Compared to the 1980’s, the time from the first symptoms to the determination of the final diagnosis of osteosarcoma has nearly doubled, extending from 3 to 5 months. Five or more years after the start of treatment, 65% of patients from the 2000-2005 Group survived, compared to 30% of patients treated in 1980-1985. Discussion: The authors’ results coincide with literature data on the increasing survival rates of osteosarcoma patients. The improved clinical results are due to more effective chemotherapy for osteosarcoma. The authors believe that the results could be even better had the time to primary diagnosis of the malignant bone disease been sustained. |