Léčba poruch dýchání vázaných na spánek u pacientů s onemocněním kardiovaskulárního systému

Title in English Treatment of respiratory disorders linked to sleep in patients with cardiovascular system
Authors

MATUŠKA Pavel KÁRA Tomáš HOMOLKA Pavel BĚLEHRAD Miloš LUDKA Ondřej SOUČEK Miroslav

Year of publication 2013
Type Article in Periodical
Magazine / Source Kardiologická revue
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords sleep related breathing disorders; obstructive sleep apnoea; central sleep apnoea; therapy
Description Treatment of sleep related breathing disorders in patients with cardiovascular system diseases. Sleep related breathing disorders are divided into two basic types: obstructive sleep apnoea and centra' sleep apnoea. A specific form is a socalled mixed sleep apnoea. Sleep related obstructive breathing disorders are caused by the narrowing or collapse of the upper airway and cause snoring syndrome, increased upper airway resistance syndrome and obstructive sleep apnoea. Pathophysiology of central sleep apnoea is complex; in hemodynamically contingent forms of central sleep apnoea (heart fallure) there is an increase in pulmonary wedge blood pressure and a change of chemoreflex sensitivity. In the treatment of obstructive sleep apnoea, the first choice of treatment is permanent positive airway pres-sure with the BiPAP, In case of intolerance, other options such as orthodontic or surgical treatment can be used, In the treatment of central sleep apnoea, the fundamental principle is maximal pharmacological and regimen treatment for prevention of heart failure, combined with adaptive servoventilation. Other possibilities include cardiac resynchronization therapy, controlled rehabilitation, and oxygen inhalation therapy. However, in many patients with severe forms of heart failure, central sleep apnoea disappears atter cardiac transplantation ar the introduction of mechanical cardiac support. This article summarises the basic principles of treatment of both types oř sleep related breathing disorders.

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