Trefoil Factor 1 as a marker of mucosal damage of the gastrointestinal tract in children with sepsis
| Authors | |
|---|---|
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | Biomarkers |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.3109/1354750X.2013.783116 |
| Field | Microbiology, virology |
| Keywords | Children; gut; mortality; sepsis; trefoil factor |
| Description | Intestinal ischemia and reperfusion is a common pathway for many diseases in children. The objective of our study was an analysis of Trefoil factor 1 levels dynamics in patients with SIRS or septic condition during a 5-day period. Analysis of TFF1 levels dynamics revealed that TFF1 levels kept steady state during the 5-day period. TFF1 levels were similar in patients with SIRS, sepsis and severe sepsis. Significantly higher levels of TFF1 were in patients with septic shock and MODS. |