Spoločné neurobiologické mechanizmy depresie a metamfetamínovej závislosti

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Title in English Common neurobiological mechanisms of depression and methamphetamine addiction


Year of publication 2014
Type Article in Periodical
Magazine / Source Alkoholizmus a drogové závislosti
MU Faculty or unit

Faculty of Medicine

Field Pharmacology and pharmaceutical chemistry
Keywords addiction; depression; psychostimulants; metamphetamine
Description Drug addiction and depression is the most common comorbidity, especially in case of secondary drug addiction of patients with depression. High comorbidity in population (30-50 %) may reflect shared neurobiogical abnormalities, aberrant neuroadaptation to acute drug effect leading to neurochemical changes, which have common elements with abnormalities connected to depression. Article presents review of neurobiological background of drug addiction and depression focused on amfetamine-like psychostimulants.
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