Motor cortex plasticity and excitability in Parkinson's disease

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Authors

BAREŠ Martin KAŇOVSKÝ Petr REKTOR Ivan

Year of publication 2014
Type Article in Periodical
Magazine / Source Clinical Neurophysiology
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1016/j.clinph.2014.01.032
Field Neurology, neurosurgery, neurosciences
Keywords INTRACORTICAL INHIBITION; PAIRED TMS; MODULATION
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Description We read with great interest the study by Kacar et al., concerning exposure to dopaminergic medication and motor cortex plasticity and excitability in Parkinson's disease (PD).The authors used a paired associative protocol (PAS), short-interval intracortical inhibition (SICI), and intracortical facilitation (1CF) to measure the sensory-motor plasticity. We would like to discuss the observation that there was no significant interaction between facilitatory sensory-motor plasticity and the features of motor cortex excitability in PD. This observation indicates that long-term treatment does not seem to change the underlying physiology of the disease.
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