Structural Biology in Use : NMR, X-ray and Molecular Dynamics Modeling in Study on Multistep Phosphorelay Signaling in Plants

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Authors	DEGTJARIK Oksana DOPITOVÁ Radka PEKÁROVÁ Blanka KLUMPLER Tomáš HORÁK Jakub BORKOVCOVÁ Petra NEJEDLÁ Eliška ŘEHA David PUEHRINGER Sandra OTRUSINOVÁ Olga JANSEN Séverine KUTÝ Michal WEISS Manfred S. SKLENÁŘ Vladimír MAREK Jaromír PAPOUŠKOVÁ Veronika ŽÍDEK Lukáš KUTÁ-SMATANOVÁ Ivana JANDA Lubomír HEJÁTKO Jan
Year of publication	2014
Type	Article in Proceedings
Conference	6. Metodické dny
MU Faculty or unit	Central European Institute of Technology
Citation
Web	http://wwwueb.asuch.cas.cz/methods/files/Methods_2014/Sbornik_Methods_2014_web_komplet.pdf
Field	Botany
Description	In multistep phosphorelay (MSP) pathway, the His-containing phosphotransmitters encoded by AHP genes in Arabidopsis act as signaling intermediates integrating signaling inputs from diverse sensor histidine kinases In comparison to prototypical two-component signaling in bacteria displaying high level of specificity, the level of specificity in related plant MSP signaling remained unclear Here I will describe our results employing both experimental and computational approaches in the identification of structural determinants of specificity in MSP signaling in Arabidopsis
Related projects:	Strukturní princip specificity přenosu signálu v rostlinách: síť interakcí příjímačové domény histidinkinas u Arabidospis CEITEC - Central European Institute of Technology