The effect of type 2 diabetes on selected clinical parameters and disease outcome in patients with colorectal cancer

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Authors

PÁCAL Lukáš VALÍK Dalibor MALÚŠKOVÁ Denisa JARKOVSKÝ Jiří KLIKA Petr OBERMANNOVÁ Radka DUŠEK Ladislav KAŇKOVÁ Kateřina

Year of publication 2017
Type Conference abstract
Citation
Description Recent epidemiological evidence indicates increased incidence of certain cancer types in patients with type 2 diabetes mellitus (T2DM), worse outcomes and also certain modifying effect of various glucose-lowering therapies. Given the population prevalence of both T2DM and colorectal cancer (CRC) their relationship is particularly relevant. Study objective was to analyse tumour-, patient- and treatment-related characteristics explaining possible difference in selected outcomes between CRC subjects with and without pre-existing diabetes by means of in-depth epidemiological analysis of all consecutive patients diagnosed and treated for CRC over the past 10 years (stratified by the presence/absence of T2DM) in the largest cancer centre in Czech Republic - Masaryk Memorial Cancer Institute (MMCI) in Brno.
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