Pyrazolotriazines as inhibitors of nucleases

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Authors

PARUCH Kamil CARBAIN Benoit, Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

Year of publication 2017
Type Patent
MU Faculty or unit

Faculty of Science

Publisher European Patent Office
State Germany
Patent's number EP2957562
Web https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20171220&DB=&locale=en_EP&CC=EP&NR=2957562B1&KC=B1&ND=4#
Description The present invention relates to substituted heterocycles as inhibitors of nudeases MUS81 and MRE11, pharmaceutical compositions containing the compounds, and pharmaceutical use of the compounds and compositions in the treatment of the diseases such as, for example, cancer.

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