Cerebellum and dystonia: The story continues. Will the patients benefit from new discoveries?

Authors

BAREŠ Martin FILIP Pavel

Year of publication 2018
Type Article in Periodical
Magazine / Source Clinical Neurophysiology
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1016/j.clinph.2017.10.007
Keywords Cerebellum; dystonia
Description When reading the recent paper of Avanzino and colleagues with cogent evidence supporting a possible role of the cerebellum in the expression of the clinical phenotype in dystonia (Avanzino et al., 2018, this issue of Clinical Neurophysiology), I could not resist to feel reminded of an invited review paper published in 2013 in the Clinical Neurophysiology, where we provided a state-of-the-art overview of cerebellar involvement in dystonia, even with possible therapeutic targets for dystonic patients in the future (Filip et al., 2017). The last couple of years have offered to me a lot of discussions on this emerging issue, positive, negative as well as neutral, during scientific sessions organized both nationally and internationally, as the traditional view of the pathophysiology of dystonia being linked mainly to basal ganglia was challenged more and more.

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