Léčba humorálních imunodeficiencí

Title in English Treatment of antibody immunodeficiency


Year of publication 2019
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Web https://www.prolekare.cz/casopisy/vnitrni-lekarstvi/2019-2-1/lecba-humoralnich-imunodeficienci-108793
Keywords antibiotic prophylaxisanti; body immunodeficiency; immunoglobulin replacement treatment
Description The basis of treatment of patients with hypogammaglobulinemia, primary or secondary, is immunoglobulin replacement. Current immunoglobulin derivates contain highly purified IgG from healthy human donors. Intravenous or subcutaneous route are almost exclusively used at present. The treatment must be individualized. Adequate doses of immunoglobulin derivates must be administered to avoid frequent and severe infections of the respiratory tract. Antibiotic prophylaxis may be alternative and complementary treatment to immunoglobulin substitution.
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