Metodologie měření kognitivního deficitu u depresivní poruchy

Title in English Methodology of cognitive impairment assessment in depressive disorder


Year of publication 2020
Type Article in Periodical
Magazine / Source Ceska a slovenska neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Keywords depressive disorder; cognitive dysfunction; psychological tests
Description This review article summarizes current information about cognitive impairment present in most of the patients with major depression. Cognitive impairment could be considered as one of the primary group of symptoms of depressive disorder and is one of the main factors in functional impairment in this patient population. Cognitive dysfunction affects more cognitive domains, is heterogeneous and is both subjective and objective. These facts complicate basic screening. There is no widely accepted consensus in the choice of test methods and in guidelines on cognitive assessment in depressive disorder. Tests which are mostly used for cognitive assessment in depressive disorder, were not created for this patient population. Moreover, basic screening methods such as Mini Mental State Examination (MMSE),Addenbrooke Cognitive Examination (ACE-R), or Montreal Cognitive Assessment (MoCA) are not sufficient in their sensitivity and specificity. Tests which appear more suitable in this disorder are those measuring cognitive domains most affected in depressive disorder - especially episodic memory, executive functions and processing speed. Test methods developed primarily for patients with a depressive disorder are University of California San Diego Performance-Based Skills Assessment (UPSA), THINC-Integrated Tool (THINC-it) and Screen for Cognitive Impairment in Psychiatry-Depression (SCI-P). Further research should address mostly systematic screening and assessment of cognitive impairment specific for depressive disorder and its changes.

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