Mukoaktivní léčiva jako podpůrná terapie zánětlivých onemocnění dýchacích cest

Title in English Mucoactive drugs as a supportive therapy for inflammatory diseases of the respiratory tract


Year of publication 2021
Type Article in Periodical
Magazine / Source Farmakoterapeutická revue
MU Faculty or unit

Faculty of Medicine

Keywords mucoactive drugs; inflammation; SARSCoV2
Description The article provides a pharmacological overview of mucoactive drugs in connection with their use in acute and chronic airway inflammation. The use of mucolytics in chronic inflammatory diseases of the respiratory system appears to be safe and provides a clear, albeit moderate benefit. In connection with the current epidemiological situation, the use of mucolytics in acute respiratory diseases, especially COVID19, is more emphasized. Few drugs have been shown in vitro, or in silico some potential to inhibit SARSCoV2 entry and replication, however, reliable clinical data are not available so far.
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