Endoscopic and medical therapy of gastric antral vascular ectasia: case series and review of available methods
| Authors | |
|---|---|
| Year of publication | 2021 |
| Type | Article in Periodical |
| Magazine / Source | Gastroenterologie a hepatologie |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.csgh.info/cs/clanek/endoskopicka-a-medikamentozni-terapie-cevnich-ektazii-zaludecniho-antra-gave-serie-kazuistik-a-prehled-metod-11235 |
| Doi | http://dx.doi.org/10.48095/ccgh2021221 |
| Keywords | gastric antral vascular ectasia; argon plasma coagulation; endoscopic band ligation; thalidomide; gastrointestinal bleeding |
| Description | Gastric antral vascular ectasia (GAVE) is an uncommon diagnosis leading to chronic iron deficiency anaemia caused by occult or overt gastrointestinal bleeding. The mainstay of the therapy is based on endoscopic therapy using endoscopic thermal methods – particularly argon plasma coagulation and others – radiofrequency ablation, coagulation or cryotherapy. Endoscopic band ligation presents satisfying results as well. Pharmacotherapy aiming at reduction of the development of new vascular lesions and reduction of blood flow in them could be considered in patients refractory to endoscopic treatment. We present a review of available endoscopic and non-endoscopic methods for GAVE therapy and our experience with the therapy of refractory GAVE using a combination of endoscopic methods and thalidomide on case series. The algorithm for GAVE therapy is proposed. |