Izolovaná infiltrace ledviny suspektními leukemickými buňkami - kazuistika s komplexní diferenciální diagnostikou neobvyklého stavu
| Title in English | Isolated kidney infiltration by suspected leukemic cells - complex differential diagnostics and an unusual case report |
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| Authors | |
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | Transfuze a hematologie dnes |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.prolekare.cz/casopisy/transfuze-hematologie-dnes/2022-1-14/izolovana-infiltrace-ledviny-suspektnimi-leukemickymi-bunkami-kazuistika-s-komplexni-diferencialni-diagnostikou-neobvykleho-stavu-130303 |
| Doi | http://dx.doi.org/10.48095/cctahd2022prolekare.cz5 |
| Keywords | acute kidney injury; acute myeloid leukaemia; fever of unknown origin; kidney leukemic infiltration; myelosarcoma; tubulointerstitial nephritis |
| Attached files | |
| Description | This article describes a case of highly suspected isolated diffuse kidney infiltration by myeloid leukemic cells, without primary bone marrow involvement or any pathological imaging findings in a patient presenting with fever of unknown origin, acute kidney injury, microcytic anaemia, weight loss, anorexia, dry cough and mild splenomegaly. This complex diagnostic process thus required repeated biopsy of both bone marrow and kidney, which subsequently ruled out leukemic infiltration. The presenting symptoms and pathological laboratory findings responded promptly to corticosteroid treatment, and our patient was finally diagnosed with tubulointerstitial nephritis. |