REZUM. Od prvního nápadu přes experiment a klinické studie až k běžné klinické praxi

Title in English REZUM. From the initial idea, through experiments and clinical studies to everyday clinical practice

PACÍK Dalibor WASSERBAUER Roman VARGA Gabriel VÍT Vítězslav FEDORKO Michal

Year of publication 2021
Type Article in Periodical
Magazine / Source Česká urologie
MU Faculty or unit

Faculty of Medicine

Keywords Benign prostatic hyperplasia; minimally invasive treatment; REZUM; lower urinary tract symptoms
Description Goal: To evaluate medium term results of treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) using the REZUM method. Material and methods: A cohort of patients (N 177) with medium to severe LUTS were treated with the REZUM method from December 2019 until June 2021 and prospectively followed up. Before treatment all patients filled out IPSS and OABv8 questionnaires and underwent uroflometry, transrectal ultrasonography, urine examination and PSA test. These parameters were repeated 3 months and 1 year after procedure and were statistically evaluated. Results: Evaluation of symptoms after 3 months and one year were finished by 170 patients and 139 patients, respectively. Significant improvement (p < 0.001 was observed in IPSS score after 3 months and one year (median 22 vs 6.9 vs 7), in QoL score (median 4 vs 1.1 vs 1.3), OABv8 (median 17 vs 5.4 vs 6). Significant increase was observed also in Qmax (median 6.9 vs 19 vs 17.3), Qave (median 3,0 vs 9.8 vs 8.9), voided volume (median 170 vs 251 vs 289) and decrease in post voided volume (median 125 vs 0 vs 0). Significant decrease was also observed in prostate volume (median 59 vs 37.2 vs 39) and total PSA (median 2.8 vs 1.9 vs 1.9). Conclusion: REZUM is a safe and effective method in treatment LUTS due to BPH after one year follow­-up.

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