Metal Oxide Laser Ionization Mass Spectrometry Imaging of Fatty Acids and Their Double Bond Positional Isomers

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Authors

KOKTAVÁ Monika VALÁŠEK Jan BEZDEKOVÁ Dominika PRYSIAZHNYI Vadym ADAMOVÁ Barbora BENEŠ Petr NAVRÁTILOVÁ Jarmila HENDRYCH Michal VLČEK Petr PREISLER Jan BEDNAŘÍK Antonín

Year of publication 2022
Type Article in Periodical
Magazine / Source Analytical Chemistry
MU Faculty or unit

Faculty of Science

Citation
Web https://pubs.acs.org/doi/10.1021/acs.analchem.2c00551
Doi http://dx.doi.org/10.1021/acs.analchem.2c00551
Keywords ozone; fatty acids; metal oxide; metal oxide laser ionization; MOLI MS; mass spectrometry imaging; MSI; double bond position; lipid isomers
Description The article presents a novel combination of metal oxide laser ionization mass spectrometry imaging (MOLI MSI) technique with off-line lipid derivatization by ozone for the detection of fatty acids (FA) and their carbon-carbon double bond (C=C) positional isomers in biological tissues.
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