The effects of cannabinoid CB1 receptor antagonist AM 251 on locomotor/exploratory behaviour and body weight in mice
| Authors | |
|---|---|
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | European Neuropsychopharmacology |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | body weight; AM 251; locomotor/exploratory behaviour; mice |
| Description | The effects of the cannabinoid CB1 receptor antagonist AM 251 were assessed in adult, non-obese male mice. The changes in the behaviour recorded were aimed on locomotor/exploratory activity of mice in the open field test. The daily administration of AM 251 reduced dose-dependently and significantly body weight, while did not significantly affect locomotor/exploratpry activities neither after acute nor repeated administration. |
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