Ecstasy induces both initiation and expression of behavioural sensitization to its stimulatory effects in mice.


LANDA Leoš ŠLAIS Karel ŠULCOVÁ Alexandra

Year of publication 2005
Type Article in Periodical
Magazine / Source European Neuropsychopharmacology
MU Faculty or unit

Faculty of Medicine

Field Pharmacology and pharmaceutical chemistry
Keywords behavioural sensitization; ecstasy; open field; mice
Description The results showed: a) significant stimulatory influence of MDMA after the acute administration, b) development of significant sensitization after MDMA repeated treatment, c) expression of sensitization after MDMA challenge dose given after 6 days of washout from the repeated MDMA treatment.
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