Basic fibroblast growth factor and its receptors in human embryonic stem cells
| Authors | |
|---|---|
| Year of publication | 2005 |
| Type | Article in Periodical |
| Magazine / Source | Folia histochemica et cytobiologica |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | stem cells |
| Description | Human embryonic stem cells (hESCs) are pluripotent stem cells with long-lasting capacity to self-renew and differentiate into various cell types of endodermal, ectodermal or mesodermal origin. The purpose of this review is to summarize recent data on the expression of FGFs and their receptors in hESCs, and critically evaluate the potential effects of FGF signals for their undifferentiated growth and/or differentiation in context with our current understanding of FGF/FGFR biology. |