Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice


LANDA Leoš ŠLAIS Karel ŠULCOVÁ Alexandra

Year of publication 2006
Type Article in Periodical
Magazine / Source Neuroendocrinology Letters
MU Faculty or unit

Faculty of Medicine

Field Pharmacology and pharmaceutical chemistry
Keywords methamphetamine; cannabinoids; behavioural sensitization; locomotion; mice
Description Methamphetamine produced significant sensitization to its stimulatory effect on locomotion. Methanandamide pre-treatment elicited cross-sensitization to methamphetamine effect, whereas pre-treatment with JWH 015 did not. Combined pre-treatment with methamphetamine+AM 251 suppressed sensitization to methamphetamine.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info