Markers of extracellular matrix remodeling, oxidative stress and inflammation in patients with acute myocardial infarction

Authors

TOMANDL Josef PAŘENICA Jiří KALA Petr POLOCZEK Martin TOMAN Ondřej TÁBORSKÁ Eva ŠPINAR Jindřich ELBL Lubomír

Year of publication 2007
Type Article in Periodical
Magazine / Source Clinical Chemistry and Laboratory Medicine
MU Faculty or unit

Faculty of Medicine

Citation
Field Biochemistry
Keywords acute myocardial infarction; ECM; inflammation; oxidative stress
Description Recent data suggest that inflammation, oxidative stress and remodeling of extracellular matrix may be associated with the development of heart failure. We assessed the association between circulating levels of soluble intercellular adhesion molecule-1 (sICAM-1), tumor necrosis factor alpha, malondialdehyde (MDA), metalloproteinase-2 and 9 (MMP) and their tissue inhibitor (TIMP-1) in patients with acute myocardial infarction.
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