Behavioural sensitization to methamphetamine affects expression of cannabinoid CB1 receptors in mouse midbrain.

Authors

LANDA Leoš JURAJDA Michal

Year of publication 2007
Type Article in Periodical
Magazine / Source Behavioural Pharmacology
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords behavioural sensitization; methamphetamine; PCR
Description The behavioural part of experiment showed stimulatory influence of methamphetamine (Met) after the acute administration and initiation of sensitization to Met after repeated treatment. Real-time PCR results showed increased CB1 mRNA expression after Met first dose followed by decrease in CB1 mRNA expression after the last dose of repeated treatment.
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