Behavioural sensitization to methamphetamine affects expression of cannabinoid CB1 receptors in mouse midbrain.
|Year of publication||2007|
|Type||Article in Periodical|
|Magazine / Source||Behavioural Pharmacology|
|MU Faculty or unit|
|Field||Pharmacology and pharmaceutical chemistry|
|Keywords||behavioural sensitization; methamphetamine; PCR|
|Description||The behavioural part of experiment showed stimulatory influence of methamphetamine (Met) after the acute administration and initiation of sensitization to Met after repeated treatment. Real-time PCR results showed increased CB1 mRNA expression after Met first dose followed by decrease in CB1 mRNA expression after the last dose of repeated treatment.|