Acute and repeated exposure to methamphetamine changes expression of CB1 receptor in mesencephalon of the mouse brain

Authors

LANDA Leoš JURAJDA Michal

Year of publication 2007
Type Article in Periodical
Magazine / Source European Neuropsychopharmacology
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords PCR; behavioural sensitization; methamphetamine; cannabinoids; CB1 receptor; mesencephalon
Description Real-time PCR results showed increased CB1 mRNA expression after both methamphetamine and methanandamide first doses followed by decrease in CB1 mRNA expression observed after the challenge dose of methamphetamine, i.e. in sensitized animals.
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