Haplotype analysis of interleukine 18 (IL-18) gene in Czech patients with allergic asthma

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Authors

IZAKOVIČOVÁ HOLLÁ Lydie SCHÜLLER Marcel KINDLOVÁ Dagmar ZNOJIL Vladimír

Year of publication 2008
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description To test a possible role of IL-18 gene polymorphisms in a Czech population, case-control study including 284 patients with allergic asthma and 312 healthy control subjects was performed. Our results indicate that the three promoter polymorphisms in the IL-18 gene act in a cooperative fashion and suggest that IL-18 haplotypes could play a role in the pathogenesis of allergic asthma in a Czech population.
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