Markers of oxidative stress in patients with acute heart failure following acute myocardial infarction
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Proceedings |
| Conference | Cor et Vasa - Supplementum |
| MU Faculty or unit | |
| Citation | |
| Field | Biochemistry |
| Keywords | oxidative stress; acute myocardial infarction; acute heart failure; malondialdehyde |
| Description | Oxidative stress and persistent inflammation are implicated in the progression of heart failure. The aim of the study was to investigate selected parameters of oxidative stress (malondialdehyde, vitamins A and E and tumor necrosis factor alpha) in patients with acute heart failure after acute myocardial infarction. Plasma values of vitamins were almost within reference interval. Levels of malondialdehyde and TNF alpha were elevated in 18 and 46 % patients on admission, respectively. Level of malondialdehyde correlated positively with TNF alpha and vitamin A and level of TNFalpha correlated negatively with vitamin E on admission. In contrast to these correlations, there were no significant relationships between measured parameters and LV ejection fraction. |
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